In vitro repair of apurinic sites in DNA.

نویسندگان

  • W G Verly
  • F Gossard
  • P Crine
چکیده

Apurinic sites disappear from DNA during an incubation of the DNA with the Escherichia coli endonuclease specific for apurinic sites, DNA polymerase I (EC 2.7.7.7.), and T4 ligase (EC 6.5.1.1). Omission of any one of these three enzymes and, in particular, omission of the endonuclease specific for apurinic sites prevents this in vitro repair.

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عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 71 6  شماره 

صفحات  -

تاریخ انتشار 1974